Iron status, S-ferritin, and hemoglobin (Hb) were assessed in a population survey in 1994 (DAN-MONICA 10) comprising 1332 Caucasian Danish men equally distributed in age cohorts of 40,50,60 and 70 years.
Blood donors (n=186) had lower S-ferritin, median 76 mug/l, than nondonors, median 169 mug/l (p<0.0001).
S-ferritin in donors was inversely correlated with the number of phlebotomies (rs=-0.57, p<0.0001).
S-ferritin in nondonors (n=1146) was similar in men 40-60 years of age, median 176 mug/l, and subsequently decreased at 70 years of age to a median of 146 mug/l (p=0.01).
In the entire series, the prevalence of small iron stores (S-ferritin 16-32 mug/l) was 2.7%, that of depleted iron stores (S-ferritin<16 mug/l) 0.45%, and that of iron deficiency anemia (S-ferritin<13 mug/l and Hb<129 g/l) 0.15%. Among nondonors, the prevalence of iron overload (S-ferritin>300 mug/l) was 20%. S-ferritin in nondonors correlated with body mass index (rs=0.19, p=0.0001) and with alcohol intake (rs=0.26, p=0.0001).
In the entire series, 28% of the subjects took supplemental iron (median 14 mg ferrous iron daily).
Iron supplements had no influence on iron status.
Nondonors (n=170) treated with acetylsalicylic acid had lower S-ferritin, median 136 mug/l, than nontreated, median 169 mug/l (p<0.001) and those treated with H2-receptor antagonists (n=30) had lower S-ferritin, median 142 mug/l, than nontreated, median 171 mug/l (p<0.04). (...)
Mots-clés Pascal : Déficit, Fer, Surcharge, Don sang, Ethanol, Supplémentation, Prévalence, Epidémiologie, Danemark, Europe, Mâle, Adulte, Homme, Personne âgée, Trouble métabolisme
Mots-clés Pascal anglais : Deficiency, Iron, Overload, Blood donation, Ethanol, Supplementation, Prevalence, Epidemiology, Denmark, Europe, Male, Adult, Human, Elderly, Metabolic disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0464879
Code Inist : 002B22E03. Création : 22/03/2000.