To evaluate prospectively the health risk of wine and beer drinking in middle-aged men in the area of Nancy, France.
Prospective cohort study.
A total of 36 250 healthy men who underwent comprehensive health appraisals in a center of preventive medicine between January 1,1978, and December 31,1983.
Main Outcome Measures
Education, professional and leisure activities, and smoking and drinking habits were evaluated using a questionnaire.
Blood pressure and mean corpuscular volume and gamma-glutamyltransferase, glucose, and serum cholesterol levels were routinely measured, and electrocardiography was routinely performed.
We recorded mortality from all causes and specific causes during a 12-to 18-year follow-up across categories of baseline alcohol consumption.
Of the subjects, 28% drank beer, 61% drank wine but no beer, and 11% were abstainers ; there was not much difference between social classes.
During the follow-up, 3617 subjects died
The relative risk of death was estimated by the Cox proportional hazards model using nondrinkers as the reference and adjusting for 4 or 5 covariables.
Moderate intake of both wine and beer was associated with lower relative risk for cardiovascular diseases ; the risk was more significant with the intake of wine.
For all-cause mortality, only daily wine intake (22-32 g of alcohol) was associated with a lower risk (0.67 ; 95% confidence interval, 0.58-0.77 ; P<. (...)
Mots-clés Pascal : Homme, Mâle, Age mûr, Est, France, Europe, Vin, Bière, Mortalité, Facteur risque, Appareil circulatoire pathologie, Alcool
Mots-clés Pascal anglais : Human, Male, Middle age, East, France, Europe, Wine, Beer, Mortality, Risk factor, Cardiovascular disease, Alcohol
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0461127
Code Inist : 002B13A03. Création : 22/03/2000.