Hold everything ! Holding policies for protecting plasma supplies.
In spite of advances in testing technologies for detecting infections such as human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV). occasionally blood or plasma is collected that is potentially infectious, but is not detected as such by existing screening tests.
We consider the effect of a holding policy for further reducing the number of potentially infectious units that are released for fractionation.
The policy dictates a holding period during which all donated units are stored.
If a donor tests positive for the infection in question at a subsequent donation. then all of that donor's units currently in storage are discarded.
Otherwise, donated units are released at the end of the holding period.
In the case of a single disease, we determine optimal holding periods as well as policies that are as effective as the best screening tests currently available.
Mots-clés Pascal : Plasma, Sang, Prélèvement, Contamination, Facteur risque, Politique sanitaire, Donneur, Analyse avantage coût, Processus renouvellement, Maladie sexuellement transmissible
Mots-clés Pascal anglais : Plasma, Blood, Samplings, Contamination, Risk factor, Health policy, Donor, Cost benefit analysis, Renewal process, Sexually transmitted disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0460922
Code Inist : 002B30A01C. Création : 22/03/2000.