Background There is conflicting evidence about the frequency of adverse pregnancy outcomes among women with schizophrenia.
Aims To investigate the risk of preterm birth, low birth weight and intra-uterine growth retardation among women with schizophrenia.
Method Atotal of 2212 births to 1537 women with schizophrenia in Denmark were compared with a random sample of all deliveries in Denmark in 1973-1993 (122 931 births to 72 742 women).
Results The children of women with schizophrenia were at increased risk of preterm delivery (relative risk=1.46,95% CI=1.19-1.79), low birth weight (relative risk=1.57,95% CI=1.36-1.82) and small for gestational age (relative risk=1.34,95% CI=1.17-1.53).
Conclusions Women with schizophrenia are at increased risk of adverse pregnancy outcome.
This may be associated with an increased mortality and general morbidity and risk of schizophrenia in their children.
Declaration of interest Supported byTheodore and Vada Stanley Foundation, NIHM grant no.
MH 53188, Helsefonden, Statens Sundhedsvidenskabelige Forskningsrad.
Mots-clés Pascal : Schizophrénie, Mère, Gestation, Facteur risque, Accouchement prématuré, Complication, Nouveau né, Homme, Epidémiologie, Prévalence, Santé mentale, Environnement social, Danemark, Europe, Femelle, Prématuré, Psychose
Mots-clés Pascal anglais : Schizophrenia, Mother, Pregnancy, Risk factor, Premature delivery, Complication, Newborn, Human, Epidemiology, Prevalence, Mental health, Social environment, Denmark, Europe, Female, Premature, Psychosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0456659
Code Inist : 002B20F02. Création : 22/03/2000.