Objective To compare the frequency of reflux oesophagitis and hiatus hernia in dyspeptic patients in England with that in Singapore.
Design Demographic, clinical and endoscopic findings in consecutive dyspeptic patients seen in England and Singapore by the same clinician were compared.
The association of various factors with the occurrence of hiatus hernia and oesophagitis was analysed by logistic regression.
Setting District general hospital in England and university hospital in Singapore.
Participants The English series comprised 212 consecutive patients, and 173 patients were seen in Singapore.
Results Reflux oesophagitis and hiatus hernia were found in 52 (25%) and 50 (49%) of the English patients, and 12 (6%) and 7 (4%) of the Singapore patients, respectively (P<0.005 in each case).
Race, body mass index and age were independently associated with hiatus hernia (odds ratios 3.07,1.08 and 1.04, respectively).
The risk factors for oesophagitis were race, sex, body mass index and age (odds ratios 4.04,2.37,1.1.1 and 1.02, respectively).
If hiatus hernia was included in the analysis, the risk factors were hiatus hernia, sex, race and body mass index (odds ratios 20.10,3.07,2.81 and 1.09, respectively).
Conclusions Reflux oesophagitis and hiatus hernia are more common in English dyspeptic patients compared to those in Singapore.
The most important risk factor for both oesophagitis and hiatus hernia is race.
Mots-clés Pascal : Dysphagie, Pathogénie, Incidence, Reflux gastrooesophagien, Prédisposition, Origine ethnique, Hernie hiatale, Etude comparative, Homme, Angleterre, Grande Bretagne, Royaume Uni, Europe, Singapour, Asie, Appareil digestif pathologie, Oesophage pathologie, Estomac pathologie
Mots-clés Pascal anglais : Dysphagia, Pathogenesis, Incidence, Gastroesophageal reflux, Predisposition, Ethnic origin, Hiatus hernia, Comparative study, Human, England, Great Britain, United Kingdom, Europe, Singapore, Asia, Digestive diseases, Esophageal disease, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0449803
Code Inist : 002B13A03. Création : 22/03/2000.