Colorectal cancers emerging after a negative Haemoccult II (r) are described in the context of a first round of mass screening in the Department of Calvados (France), from April 1991 to the end of December 1994.
People with a cancer occurring after a negative test until 31 December 1995 were identified by a local cancer registry.
Incidence was calculated and the programme sensitivity was estimated.
The incidence of cancer emerging after a negative test was 57. 7 per 100 000, i.e. half of the calculated incidence in the reference group (141.6 per 100 000).
These cancers did not differ from those of either the non-responder or reference groups, in particular for the stage of extension.
The programme sensitivity was globally higher than that estimated in European trials : 77.2,66.3 and 55.9%, 1,2 and 3 years after the test respectively.
Programme sensitivity was higher for distal colon cancer 1 year after the test, which is probably due to the relatively slow growth of this subsite.
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Sang, Fèces, Dépistage, Faux négatif, Sensibilité, Programme sanitaire, France, Europe, Homme, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Blood, Feces, Medical screening, False negative, Sensitivity, Sanitary program, France, Europe, Human, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0448913
Code Inist : 002B13B01. Création : 22/03/2000.