This study aimed to investigate the relation between environmental influences such as arsenic, cadmium, lead, and mercury, as well as environmental tobacco smoke, pet keeping, and heating systems on the prevalence of atopic eczema.
Therefore, a multicenter cross-sectional study of school children aged 5-14 years, including a standardized questionnaire, blood and urine analyses, and a dermatological examination, was undertaken.
A cases-control approach was chosen in order to identify relevant risk factors.
A total of 2200 school children (response 79.1%) of two areas (Bitter-feld, Hettstedt) polluted by industrial activities and an agricultural control region (Zerbst) of the former German Democratic Republic were examined.
Atopic eczema as identified by dermatological examination and history was the outcome variable of interest.
Body burden of arsenic and heavy metals and questionnaire data on environmental tobacco smoke exposure, pet keeping, and heating system were investigated as potential risk factors.
The overall prevalence of atopic eczema was 2.6%, with higher prevalences in the industrial areas (2.5 and 2.9%) compared to the control area (1.6%, not significant).
Bivariate analyses did not reveal statistically significant associations between atopic eczema and tobacco smoke exposure or the body burden of arsenic and heavy metals. (...)
Mots-clés Pascal : Pollution intérieur, Toxicité, Eczéma, Enfant, Homme, Atopie, Age scolaire, Epidémiologie, Métal lourd, Installation chauffage, Equipement chauffage, Animal familier, Facteur risque, Prédisposition, Allemagne(république démocratique), Allemagne, Europe, Allergie, Immunopathologie, Peau pathologie
Mots-clés Pascal anglais : Indoor pollution, Toxicity, Eczema, Child, Human, Atopy, School age, Epidemiology, Heavy metal, Heating installation, Heating equipment, Pet animal, Risk factor, Predisposition, East Germany, Germany, Europe, Allergy, Immunopathology, Skin disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0448747
Code Inist : 002B06C04. Création : 22/03/2000.