Evaluation of surgical treatment for patients with gastric cancer who are over 80 years of age.
The aim of this study is to evaluate whether super-elderly patients (>=80) with gastric cancer may be appropriate candidates for an R2/R3 (extended) gastrectomy.
The study evaluated 1334 patients with gastric cancer treated over the past 15 years, who were over 40 years of age.
They were divided into three groups according to age : Super-elderly patients who were over 80 (group A ; n=60), those aged 60-79 (group B ; n=703) and those aged 40-59 (group C ; n=571).
The incidence of concomitant systemic disorders was higher in group A than in either group B or group C (65% vs. 53.2% vs. 34%) (p<0.0001).
The resection rates were similar (88.3% vs. 93.7% vs. 96.1%), however, the incidence of a total gastrectomy, an R2/R3 dissection, or a combined resection of other organs was much lower in group A than those in the other groups (p<0.005).
The survival curves of patients after a curative resection were not significant, however, 34.4% of the super-elderly patients died of other causes and the 5-year survival rates including other cause of death were poorer in groups A and B than those in group C (p<0.01).
In group A, patients receiving an R2/R3 dissection had a two-fold higher incidence of post-operative complications over those receiving an R0/R1 (regional) dissection, however, they also had a better prognosis whether or not other causes of death were considered. (...)
Mots-clés Pascal : Carcinome, Estomac, Evaluation, Gastrectomie, Personne âgée, Homme, Age 80-89, Facteur risque, Indication, Japon, Asie, Tumeur maligne, Appareil digestif pathologie, Estomac pathologie, Chirurgie
Mots-clés Pascal anglais : Carcinoma, Stomach, Evaluation, Gastrectomy, Elderly, Human, Age 80-89, Risk factor, Indication, Japan, Asia, Malignant tumor, Digestive diseases, Gastric disease, Surgery
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0443973
Code Inist : 002B25G02. Création : 22/03/2000.