logo BDSP

Base documentaire

  1. Carbon and hemosiderin-laden macrophages in sputum of traffic policemen exposed to air pollution.

    Article - En anglais

    In this study, we evaluated (a) quantitative modifications of dust cells and siderocytes and (b) qualitative modifications (i.e., cellular changes and inflammatory infiltrate) in sputum of 164 traffic policemen occupationally exposed to environmental pollution in an urban area.

    Such modifications were correlated with time of exposure and smoking habits.

    Seventy-three (45%) of the policemen were smokers, and a control group of 119 nonexposed individuals (24% smokers) who resided in a rural district near Perugia, Italy, were examined.

    The sputa, which was collected for 3 d, were smeared on glass slides stained according to Papanicolaou's and Perl's methods.

    The mean numbers of dust cells in the sputa policemen and the rural population were 103.8 and 12.48, respectively (p<. 0001).

    The numbers of dust cells were highest in policemen who smoked (relative risk=3.95 ; p<. 006).

    The mean numbers of siderocytes in policemen and the rural population were 0.99 and 5.31, respectively (not statistically significant, Mann-Whitney test).

    The difference between the number of subjects with hemosiderin-laden macrophages in traffic policemen and in the control group was small, but it was significant statistically (p<. 004).

    In traffic policemen, it was related to smoking and time of exposure to air pollution, whereas in the control population it was related to heart-pulmonary diseases.

    In this study, we observed a synergistic effect between smoking and environmental pollution. (...)

    Mots-clés Pascal : Pollution air, Milieu urbain, Trafic urbain, Policier, Exposition professionnelle, Médecine travail, Homme, Expectoration, Macrophage, Poussière, Exploration cytologique, Matériel biologique, Italie, Europe

    Mots-clés Pascal anglais : Air pollution, Urban environment, Urban traffic, Policeman, Occupational exposure, Occupational medicine, Human, Sputum, Macrophage, Dust, Cytologic investigation, Biological material, Italy, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0443299

    Code Inist : 002B03M02. Création : 22/03/2000.