The main aim of the study was to examine possible solvent-associated effects on the nervous system in currently employed painters.
Special attention was paid to evaluate subtle health effects.
A total of 401 painters and 209 construction workers without solvent exposure with at least 10 years of professional experience were subjected to a clinical, neurological, psychiatric, neuropsychological and neurophysiological examination.
For personal medical and occupational history, standardized questionnaires were used.
A quantitative rating of exposure was obtained by expert rating of the respective occupational history without knowledge of the individual test results.
There was no excess of somatic disorders or solvent-associated adverse effects on the nervous system.
No distinct effects of solvent exposure on nerve conduction velocities (NCV) or cognition were found.
Discrete NCV deficits in painters were not considered a sign of subclinical polyneuropathy.
Painters, however, reported an excess of specific symptoms that could be assigned to « mood and behaviour ».
The differences between specific and non-specific questionnaire outcomes on the one hand and the positive correlation between chronic exposure index and symptom scores on the other hand support the hypothesis of solvent-induced effects.
Because data is lacking on past solvent exposure, it is not possible to relate these effects to current exposure limits. (...)
Mots-clés Pascal : Solvant organique, Toxicité, Homme, Peintre en bâtiment, Industrie construction, Exposition professionnelle, Médecine travail, Epidémiologie, Allemagne, Europe, Système nerveux pathologie
Mots-clés Pascal anglais : Organic solvent, Toxicity, Human, House painter, Construction industry, Occupational exposure, Occupational medicine, Epidemiology, Germany, Europe, Nervous system diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0437926
Code Inist : 002B03L04. Création : 22/03/2000.