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  1. Fulltext. Birth Defects surveillance : Assessing the "gold standard".

    Article - En anglais



    This study assessed the sensitivity of the Metropolitan Atlanta Congenital Defects Program (MACDP) by capitalizing on the delayed receipt of a data source.


    In 1997, we reviewed the medical records of potential cases from the 1995 birth certificates that had not previously been identified by the MACDP.

    Capture-recapture methods produced an estimate of total cases.


    We identified 1149 infants with defects, including 20 exclusively from birth certificates.

    The estimated sensitivity of the MACDP when data from birth certificates were included was 86.9% (95% confidence interval [Cl]=80.6%, 91.9%) at I year after birth, increasing to 94.8% (95% CI=90.3%, 97.8%) at 2 years after birth.


    The MACDP under-estimates defects by 13% at 1 year after birth and by 5% at 2 years after birth.

    Mots-clés Pascal : Normalisation, Programme sanitaire, Dépistage, Malformation, Faux négatif, Foetus, Diagnostic, Prénatal, Foetus pathologie, Homme, Femelle, Gestation, Qualité, Sensibilité, Modèle, Intervalle confiance, Etude statistique, Gestation pathologie

    Mots-clés Pascal anglais : Standardization, Sanitary program, Medical screening, Malformation, False negative, Fetus, Diagnosis, Prenatal, Fetal diseases, Human, Female, Pregnancy, Quality, Sensitivity, Models, Confidence interval, Statistical study, Pregnancy disorders

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0436221

    Code Inist : 002B30A03B. Création : 22/03/2000.