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  1. Fulltext. Serum vitamin C concentrations and diabetes : findings from the third National Health and Nutrition Examination Survey, 1988-1994.

    Article - En anglais



    Previous studies suggested that diabetes mellitus may lower serum vitamin C concentrations, but most of these studies used clinic-based populations with established diabetes of varying duration and did not adjust for important covariates.


    Using a population-based sample and adjusting for important covariates, we asked whether serum vitamin C concentrations in persons with newly diagnosed diabetes differed from those in persons without diabetes.


    Data were obtained from the third National Health and Nutrition Examination Survey (1988-1994).

    Serum vitamin C was assayed by using reversed-phase HPLC with multiwave-length detection.

    Diabetes status (n=237 persons with diabetes ; n=1803 persons without diabetes) was determined by oral-glucose-tolerance testing of the sample aged 40-74 y. Results : After adjustment for age and sex, mean serum vitamin C concentrations were significantly lower in persons with newly diagnosed diabetes than in those without diabetes.

    After adjustment for dietary intake of vitamin C and other important covariates, however, mean concentrations did not differ according to diabetes status.


    When assessing serum vitamin C concentrations by diabetes status in the future, researchers should measure and account for all factors that influence serum vitamin C concentrations.

    Mots-clés Pascal : Analyse quantitative, Acide ascorbique, Plasma sanguin, Régime alimentaire, Diabète insulinodépendant, Diabète non insulinodépendant, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Vitamine, Alimentation, Endocrinopathie, Immunopathologie, Maladie autoimmune, Homme

    Mots-clés Pascal anglais : Quantitative analysis, Ascorbic acid, Blood plasma, Diet, Insulin dependent diabetes, Non insulin dependent diabetes, Epidemiology, United States, North America, America, Vitamin, Feeding, Endocrinopathy, Immunopathology, Autoimmune disease, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0434987

    Code Inist : 002B21E01A. Création : 22/03/2000.