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  1. Prebiotics, probiotics and human gut microbiology.

    Article, Communication - En anglais

    ECB9 European Congress on Biotechnology. Brussels, BEL, 1999/07/11.

    Because of its resident microbiota, the human colon is one of the body's most metabolically active organs.

    Gut bacteria predominantly ferment undigested food materials.

    The nature of the fermentation may have different health consequences.

    For example, the end products of carbohydrate metabolism are benign, whilst proteolytic metabolites may be toxic.

    The use of diet to fortify certain gut flora components is a popular current aspect of functional food sciences.

    In this context probiotics, prebiotics and synbiotics all have a significant role.

    Probiotics are live microbial additions to the diet ; prebiotics are foodstuffs that have a selective metabolism in the hindgut, whilst synbiotics are combinations of the two approaches.

    It has been demonstrated that each of these dietary intervention routes can have an effect on the gut flora'balance'Whilst the real health advantages remain elusive, the use of gut microflora management has a number of potentially very important effects with resistance to pathogens, effects on gut tumours and reduction in blood lipids holding much promise.

    The advent of molecular tools into gut microbiology, now offer the means to more fully explore the gut biodiversity as well as reliably track changes in response to diet.

    The near future will determine whether the full potential of probiotics, prebiotics and synbiotics can be realised.

    Mots-clés Pascal : Résistance microorganisme, Intestin pathologie, Lipide, Sang, Article synthèse, Probiotique, Aliment santé, Intestin, Microflore associée, Homme, Industrie alimentaire, Microbiologie industrielle, Tumeur maligne, Substance prébiotique, Synbiotique

    Mots-clés Pascal anglais : Microorganism resistance, Intestinal disease, Lipids, Blood, Review, Probiotic, Health food, Gut, Associated microflora, Human, Food industry, Industrial microbiology, Malignant tumor, Prebiotics, Synbiotic

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0431408

    Code Inist : 002A35D. Création : 22/03/2000.