Background Physical activity has been proposed to decrease lung cancer risk ; however, few data are available.
Further, no studies have examined specific kinds and intensities of activities.
Methods We conducted a prospective cohort study among 13 905 male Harvard University alumni (mean age, 58.3 years), free of cancer.
Men reported their walking, stair climbing and participation in sports or recreation on baseline questionnaires in 1977, and the occurrence of lung cancer on follow-up questionnaires in 1988 and 1993.
Death certificates were obtained for decedents through 1992 to determine lung cancers not previously reported.
Results During follow-up, 245 men developed lung cancer.
Adjusting for age, cigarette smoking, and body mass index, the relative risks of lung cancer associated with<4200,4200-8399,8400-12 599 and >=12 600 kJ/week of estimated energy expenditure at baseline were 1.00 (referent), 0.87 (95% CI : 0.64-1.18), 0.76 (95% CI : 0.52-1.11), and 0.61 (95% CI : 0.41-0.89), respectively ; P trend=0.0008.
Similar trends were observed among non-smokers or former smokers in 1977 (82.7% of men) as well as among those who smoked>20 cigarettes a day in 1977 (8.0%), although the findings in the latter group were not statistically significant, possibly due to the small number. (...)
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Homme, Mâle, Facteur risque, Tabagisme, Protection, Entraînement physique, Etude cohorte, Questionnaire, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Evaluation, Dépense énergétique, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Human, Male, Risk factor, Tobacco smoking, Protection, Physical training, Cohort study, Questionnaire, United States, North America, America, Epidemiology, Evaluation, Energetic cost, Respiratory disease, Lung disease, Bronchus disease
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0425946
Code Inist : 002B11A. Création : 22/03/2000.