Selecting subjects for ultrasonographic screening for aneurysms of the abdominal aorta : four different strategies.
Background We studied whether the effectiveness of ultrasound screening for abdominal aortic aneurysms could be increased by preselecting high-risk subjects, based on the presence of risk indicators for the disease.
Methods In a population-based screening programme for abdominal aortic aneurysms among 5328 subjects living in Rotterdam, The Netherlands, we studied four different strategies to select subjects for ultrasound screening of the abdominal aorta, based on risk indicators for abdominal aortic aneurysm disease.
Risk indicators used in each strategy were entered in a logistic regression model to predict the probability of an individual having an abdominal aortic aneurysm.
Using several cutoff values for the probability of a subject having an aneurysm for each strategy, we estimated the proportion of subjects that should be referred for ultrasound screening and the proportion of aneurysms that would be diagnosed by each strategy (sensitivity).
Results When a probability of 1.5% of having an aneurysm is chosen as the cutoff point above which ultrasound screening is indicated, the proportion of subjects that would be referred for screening ranged from 36% (first strategy) to approximately 50% (other strategies), while 80% (first strategy) to approximately 94% (other three strategies) of all aneurysms would be detected. (...)
Mots-clés Pascal : Anévrysme, Aorte, Aorte abdominale, Personne âgée, Homme, Dépistage, Exploration ultrason, Echographie, Efficacité, Sélection, Malade, Questionnaire, Risque, Pays Bas, Europe, Epidémiologie, Stratégie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Aorte pathologie, Artère pathologie
Mots-clés Pascal anglais : Aneurysm, Aorta, Abdominal aorta, Elderly, Human, Medical screening, Sonography, Echography, Efficiency, Selection, Patient, Questionnaire, Risk, Netherlands, Europe, Epidemiology, Strategy, Cardiovascular disease, Vascular disease, Aortic disease, Arterial disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0425944
Code Inist : 002B12B02. Création : 22/03/2000.