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  1. Low birthweight and prematurity in relation to paternal factors : a study of recurrence.

    Article - En anglais

    Background The importance of paternal determinants in the occurrence of low birthweight and prematurity is not well known.

    We investigated these outcomes in siblings and paternal half siblings as a function of changes in putative external determinants between two births in fathers who had experienced the birth of a premature and/or low birthweight (PTB/LBW) infant.

    Methods All fathers who, between 1980 and 1992, had an infant born before 37 completed weeks'gestation or weighing<2500 g and a following child were studied.

    We identified 14 147 pairs of siblings from Danish national registers.

    The recurrence risk was studied in three sub-cohorts defined by the outcome in the index child (PTB only, PTB/LBW, LBW only).

    We estimated the recurrence risk in the younger sibling according to changes of female partner, municipality type, occupation, and father's social status.

    Results The overall recurrence risk was 16.7% for preterm delivery and 16.8% for LBW.

    Changing female partner was, as expected, associated with a reduction in the recurrence risk for both outcomes (RR=0.40 ; 95% CI : 0.27-0.60 for preterm delivery and RR=0.38 ; 95% CI : 0.26-0.56 for LBW).

    None of the other studied factors was associated with changes in the recurrence risk.

    Fathers who changed partner had offspring with similar birthweight and gestational length between the three sub-cohorts, while a difference was evident in offspring to fathers whose female partner was unchanged. (...)

    Mots-clés Pascal : Poids naissance faible, Nouveau né, Homme, Facteur risque, Récidive, Père, Partenaire sexuel, Changement, Statut social, Parité, Etude cohorte, Etude longitudinale, Danemark, Europe, Epidémiologie, Evaluation, Gestation pathologie, Prématurité, Nouveau né pathologie

    Mots-clés Pascal anglais : Low birth weight, Newborn, Human, Risk factor, Relapse, Father, Sex partner, Change, Social status, Parity, Cohort study, Follow up study, Denmark, Europe, Epidemiology, Evaluation, Pregnancy disorders, Prematurity, Newborn diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0425939

    Code Inist : 002B20F02. Création : 22/03/2000.