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  1. Vertebral osteomyelitis in northern Spain. Report of 62 cases.

    Article - En anglais

    Objective The records of 62 patients with clinical and radiographic evidence of vertebral osteomyelitis and positive bacteriological diagnosis, seen between 1979 and 1996, were reviewed in order to gather data on the epidemiology and the clinical pattern displayed by patients with this condition in northern Spain.

    Results Staphylococcus aureus (15 cases), Mycobacterium tuberculosis (15 cases) and Brucella melitensis (13 cases) were the microorganisms most frequently found in our patient series.

    After improvement of the sanitary and hygienic control of food products, the role of Brucella melitensis is decreasing as a causative agent (only 3 cases in the last 6 years).

    Stapylococcus epidermidis, present in 4 cases (6.6%), should be suspected in elderly patients with previous intravenous cannulations (3 of 4 cases).

    The most frequent risk factors were alcoholism (7 cases), chronic hepatic disease (7 cases), diabetes (6 cases) and previous surgery (6 cases).

    Delay in diagnosis was high (the mean number of days between the onset of symptoms and diagnosis was 125).

    The lumbar region was the most commonly affected site.

    Neurologic involvement was present in 10 patients on admission (16%). ESR was>50 mm/hr in a high number of cases.

    Blood cultures were found to be the most valuable routine test.

    Plain x-rays were normal in 10 patients (16%) ; in 6 of them Staphylococcus aureus was the responsible organism.

    Other imaging modalities showed a high sensitivity. (...)

    Mots-clés Pascal : Ostéite, Vertèbre, Homme, Epidémiologie, Espagne, Europe, Facteur risque, Bactériose, Infection, Diagnostic, Exploration microbiologique, Traitement, Pronostic, Système ostéoarticulaire pathologie, Ostéopathie, Rachis pathologie

    Mots-clés Pascal anglais : Osteitis, Vertebra, Human, Epidemiology, Spain, Europe, Risk factor, Bacteriosis, Infection, Diagnosis, Microbiological investigation, Treatment, Prognosis, Diseases of the osteoarticular system, Bone disease, Spine disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0425413

    Code Inist : 002B05B02J. Création : 22/03/2000.