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  1. Universal prophylaxis for Chlamydia trachomatis and anaerobic vaginosis in women attending for suction termination of pregnancy : an audit of short-term health gains.

    Article - En anglais

    A previous study of infection and morbidity in 400 women attending for termination of pregnancy (TOP) had shown that 32 (8%) harboured cervical Chlamydia trachomatis and 112 (28%) had anaerobic (bacterial) vaginosis (AV).

    Fifty-three per cent of the women with preoperative C. trachomatis had AV.

    Thirty of the 32 women with chlamydial infection were followed up and 19 (63%) of these developed post-abortion upper genital tract infection, 7 of whom needed re-admission'In view of the high morbidity in women with chlamydial infection attending for TOP, anti-bacterial prophylaxis with metronidazole suppositories and oral oxytetracycline was introduced for women attending for suction termination of pregnancy (STOP).

    An audit of the clinical and financial benefits and/or losses was carried out.

    The audit of 1951 consecutive patients attending for STOP revealed that 132 (6.8%) had chlamydial infection with equivocal results reported in a further 2 patients.

    One hundred and eight of the 134 women responded to recall.

    Full genital tract infection screening was carried out in 105 of the 108 recalled patients of whom 5 had repeat positive cervical swabs for C. trachomatis, one had Trichomonas vaginalis, 24 had candidiasis and 17 had anaerobic vaginosis, none had gonorrhoea.

    Thirteen (12%) of the 108 women had pelvic infection as previously defined1, none of whom required re-admission. (...)

    Mots-clés Pascal : Chlamydiose, Bactériose, Infection, Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bactérie, Chimioprophylaxie, Oxytétracycline, Voie orale, Prévention, Métronidazole, Voie rectale, Association médicamenteuse, Avortement, Antibactérien, Antibiotique, Efficacité, Court terme, Coût, Homme, Tétracycline dérivé, Imidazole dérivé, Composé nitro, Economie santé, Gestation pathologie, Vaginose bactérienne

    Mots-clés Pascal anglais : Chlamydiosis, Bacteriosis, Infection, Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bacteria, Chemoprophylaxis, Oxytetracycline, Oral administration, Prevention, Metronidazole, Rectal administration, Drug combination, Abortion, Antibacterial agent, Antibiotic, Efficiency, Short term, Costs, Human, Tetracycline derivatives, Imidazole derivatives, Nitro compound, Health economy, Pregnancy disorders

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0418232

    Code Inist : 002B02S02. Création : 22/03/2000.