Weight change and lung function : Implications for workplace surveillance studies.
This study evaluated the relationship between weight change and longitudinal measurement of lung function among 361 men providing at least five pulmonary function lests.
The men in this study were participants in a workplace pulmonary surveillance program for subjects with exposure to refractory ceramic fibers (RCFs).
Occupational and environmental studies are generally designed to evaluate factors suspected of causing excess decline in lung function.
Failure to adequately account for all significant factors may lead to erroneous conclusions regarding change in lung function.
This study utilized two different statistical models to evaluate longitudinal changes in a cohort of RCF workers.
What was unique to this study was the modeling of longitudinally measured initial weight, weight change, and longitudinal exposure before and during the period of observation.
Results showed a strong relationship between weight gain and longitudinal loss in lung function that approximated forced vital capacity declines of 16 mL for every kilogram of weight gain per year in both models.
This value is comparable or greater in magnitude and significance to other factors known to be inversely related to lung function, such as age and pack-years smoking to time of initial testing.
In conclusion, weight gain was found to have a significant impact on longitudinal change in lung function. (...)
Mots-clés Pascal : Fonction respiratoire, Poids corporel, Lieu travail, Milieu professionnel, Homme, Etude cohorte, Programme sanitaire, Respiration, Prise poids, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Surveillance sanitaire
Mots-clés Pascal anglais : Lung function, Body weight, Work place, Occupational environment, Human, Cohort study, Sanitary program, Respiration, Weight gain, Epidemiology, United States, North America, America, Sanitary surveillance
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0416507
Code Inist : 002B30B02A. Création : 22/03/2000.