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  1. Thyroid volumes in US and Bangladeshi schoolchildren : comparison with European schoolchildren.

    Article - En anglais


    The World Health Organization (WHO) recently adopted thyroid volume ultrasonography results from European schoolchildren as the international reference for assessing iodine deficiency disorders.

    Our objective was to describe thyroid volumes measured by ultrasonography in US and Bangladeshi schoolchildren and compare these with European schoolchildren.


    Cross-sectional studies were performed in schoolchildren in the US (n=302) and Bangladesh (n=398).

    Data were collected on the following 

    Thyroid size by palpation and ultrasonography ; urinary iodine ; age :

    • Thyroid size by palpation and ultrasonography ;

    • urinary iodine ;

    • sex : weight ;

    • and height.


    Applying the new WHO thyroid volume references to the Bangladeshi children resulted in prevalence estimates of enlarged thyroid of 26% based on body surface area (BSA) and 7% based on age.

    In contrast, in the US children, the prevalence estimates were less than 1% for each reference.

    In the US children, the best single predictor of thyroid volume was BSA (R2=0.32), followed by weight (R2=0.3 1).

    Using linear regression, upper normal limits (97th percentile) of thyroid volume from US children were calculated for BSA, weight and age, and were found to be lower than the corresponding references based on BSA and age from European schoolchildren.


    In areas with malnutrition, such as Bangladesh, the BSA reference should be preferred to the reference based on age. (...)

    Mots-clés Pascal : Thyroïde, Volume, Etude comparative, Pays, Age, Sexe, Echographie, Poids corporel, Taille corporelle, Iode, Urine, Goitre, Prévalence, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Enfant, Homme, Bengla Desh, Asie, Europe, Exploration ultrason, Endocrinopathie, Thyroïde pathologie

    Mots-clés Pascal anglais : Thyroid gland, Volume, Comparative study, Countries, Age, Sex, Echography, Body weight, Body size, Iodine, Urine, Goiter, Prevalence, Epidemiology, United States, North America, America, Child, Human, Bangladesh, Asia, Europe, Sonography, Endocrinopathy, Thyroid diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0412960

    Code Inist : 002B30A01A2. Création : 22/03/2000.