Predictors of the severity of acute pancreatitis in patients with HIV infection or AIDS.
We retrospectively reviewed the charts of 54 human immunodeficiency virus (HIV) infected patients or acquired immunodeficiency syndrome (AIDS), who were hospitalized at the Bronx-Lebanon Hospital Center with acute pancreatitis between January 1993 and December 1995.
Nineteen were female and 35 were male patients.
Thirty-five (65%) of 54 patients were younger than 40 years (average age, 42 years).
Forty-eight (89%) of the patients had a CD4 count of<200 units/ml of blood.
Seventeen (32%) patients died either of complications of acute pancreatitis or of underlying disease.
The conventional prognostic criteria used to assess the severity of pancreatitis, including Ranson's and Imrie's criteria and the APACHE II system, were applied.
We determined that these criteria were not appropriate to our HIV/AIDS patients.
Only serum calcium levels at 48 h after admission and serum creatinine and blood urea nitrogen (BUN) at admission and at 48 h after admission had significant p values (<0.05).
We believe that the predictors commonly used to identify the severity of pancreatitis were not useful in these patients because of their low CD4 counts and preexisting liver and renal disease.
Mots-clés Pascal : Pancréatite, Aigu, Aggravation, SIDA, Virose, Infection, Virus immunodéficience humaine, Lentivirus, Retroviridae, Virus, Facteur prédictif, Prévalence, Article synthèse, Association, Homme, Appareil digestif pathologie, Pancréas pathologie, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : Pancreatitis, Acute, Aggravation, AIDS, Viral disease, Infection, Human immunodeficiency virus, Lentivirus, Retroviridae, Virus, Predictive factor, Prevalence, Review, Association, Human, Digestive diseases, Pancreatic disease, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0412826
Code Inist : 002B13C03. Création : 22/03/2000.