Local versus WHO/International Council for Control of Iodine Deficiency Disorders-recommended thyroid volume reference in the assessment of iodine deficiency disorders.
Iodine deficiency endemia is defined by the goitre prevalence and the median urinary iodine concentration in a population.
Lack of local thyroid volume reference data may bring many health workers to use the European-based WHO/International Council for Control of Iodine Deficiency Disorders (ICCIDD) - recommended reference for the assessment of goitre prevalence in children in different developing countries.
The present study was conducted in non-iodine-deficient areas in Malaysia to obtain local children's normative thyroid volume reference data, and to compare their usefulness with those of the WHO/ICCIDD-recommended reference for the assessment of iodine-deficiency disorders (IDD) in Malaysia.
Design and methods
Cross-sectional thyroid ultrasonographic data of 7410 school children (4004 boys, 3406 girls), aged 7-10 years, from non-iodine-deficient areas (urban and rural) in Peninsular Malaysia were collected.
Age/sex-and body surface area/sex-specific upper limits (97th percentile) of normal thyroid volume were derived.
Thyroid ultrasonographic data of similar-age children from schools located in a mildly iodine-deficient area, a severely iodine-deficient area, and a non-iodine-deficient area were also collected ; spot urines were obtained from these children for iodine determination. (...)
Mots-clés Pascal : Goitre, Prévalence, Epidémiologie, Système référence, Diagnostic, Etude comparative, Echographie, Volume, Thyroïde, Iode, Urine, Malaisie, Asie, Enfant, Homme, Endocrinopathie, Thyroïde pathologie, Exploration ultrason
Mots-clés Pascal anglais : Goiter, Prevalence, Epidemiology, Reference system, Diagnosis, Comparative study, Echography, Volume, Thyroid gland, Iodine, Urine, Malaysia, Asia, Child, Human, Endocrinopathy, Thyroid diseases, Sonography
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0412408
Code Inist : 002B30A01A2. Création : 22/03/2000.