Simultaneous determination of trace benzodiazepines from drinks by using direct electrospray probe/mass spectrometry (DEP/MS).
This study presents a novel means of rapidly determining benzodiazepines in various drinks.
Electrospray mass spectrometry with a direct probe design is used as the analytical instrument.
Samples are treated only by a simple liquid-liquid extraction prior to direct electrospray probe/mass spectrometry (DEP/MS) analysis.
The proposed method provides a relatively easy and efficient means of identifying the drugs in a very short time interval.
On average, sample analysis is completed in less than five minutes including sample pretreatment.
It is especially useful in forensic science since the technology can provide a rapid identification for unknown samples.
Thus, the method proposed herein is highly appropriate for rapidly screening a large number of samples.
Mots-clés Pascal : Benzodiazépine dérivé, Résidu, Boisson, Spectrométrie masse, Electrospray, Analyse trace, Aspect médicolégal, Analyse quantitative, Meurtre, Médecine légale, Technique, Analyse biochimique
Mots-clés Pascal anglais : Benzodiazepine derivatives, Residue, Beverage, Mass spectrometry, Electrospray, Trace analysis, Forensic aspect, Quantitative analysis, Murder, Legal medicine, Technique, Biochemical analysis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0412325
Code Inist : 002B30A10. Création : 22/03/2000.