Objectives-To identify risk factors for transmission of verocytotoxin producing Escherichia coli 0157 (VTECO157) and means of prevention.
Retrospective cohort study.
Setting-A nursery (child care centre) in North Wales.
Methods-Faeces were examined using sorbitol MacConkey agar (SMAC), with cefixime, tellurite, and rhamnose ; enrichment in modified tryptone soya broth ; and immunomagnetic separation.
Symptoms and exposure data were obtained from questionnaires to parents/guardians and children's toiletting and feeding records kept at the nursery.
» was defined as a child with verocytotoxin producing E coli 0157 isolated from faeces, or a history of haemolytic uraemic syndrome (HUS) and antibodies to E coli 0157 lipopolysaccharide, during the period 10 August to 30 September 1995.
The attack rate was 31 in 104.
Two children developed HUS.
There were higher attack rates among girls and friends who played together.
Cases were more likely to attend the nursery more frequently.
The mean number of recorded bowel motions/child/half day was 0.51 in cases and 0.21 in well children.
Child to staff ratios were high preceding and during the outbreak.
Conclusions-A sick child is the most plausible source of infection with subsequent person to person transmission. (...)
Mots-clés Pascal : Escherichia coli, Enterobacteriaceae, Bactérie, Bactériose, Infection, Entérocolite, Epidémie, Garderie enfant, Prévention, Transmission homme homme, Appareil digestif pathologie, Intestin pathologie
Mots-clés Pascal anglais : Escherichia coli, Enterobacteriaceae, Bacteria, Bacteriosis, Infection, Enterocolitis, Epidemic, Day care center, Prevention, Transmission from man to man, Digestive diseases, Intestinal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0411286
Code Inist : 002B05B02F. Création : 22/03/2000.