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  1. Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer.

    Article - En anglais

    Epidemiological evidence points to an increased risk of breast cancer in ataxia telangiectasia (AT) heterozygote women.

    Previous attempts to screen early onset or familial breast cancer patients failed to confirm an association.

    The issue of AT and late onset sporadic breast cancer remained unresolved.

    We screened 47 women who developed later onset, sporadic breast cancer for ataxia telangiectasia mutated (ATM) mutations.

    No mutations were found.

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Ataxie télangiectasie, Mutation, Gène, Epidémiologie, Canada, Amérique du Nord, Amérique, Homme, Glande mammaire pathologie, Génétique, Système nerveux pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Oeil pathologie, Peau pathologie, Immunopathologie, Maladie héréditaire, Test PTT, Gène ATM

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Ataxia telangiectasia, Mutation, Gene, Epidemiology, Canada, North America, America, Human, Mammary gland diseases, Genetics, Nervous system diseases, Cardiovascular disease, Vascular disease, Eye disease, Skin disease, Immunopathology, Genetic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0411234

    Code Inist : 002B20E02. Création : 22/03/2000.