Occupational respiratory symptoms caused by decorative flowers are seldom reported in the literature.
In out area a large portion of the population works in carnation (Dianthus caryophyllus) winter quarters, and many workers have symptoms of rhinitis and asthma related to exposition.
The purposes of this study were to investigate whether the symptoms induced by carnation were IgE-mediated and to study the possible allergens involved.
A total of 16 subjects employed in indoor carnation cultivation with symptoms during exposition time were studied along with 15 patients with allergic asthma who were not exposed to carnations and 15 healthy carnation workers used as control subjects.
Skin prick tests with carnation extract and RASTs were performed.
Protein bands were isolated by SDS-PAGE, and afterwards immunoblotting was performed to characterize the extract.
Specific nasal provocation and nonspecific bronchial provocation tests were performed for all the asthmatic patients.
Diurnal variation in peak expiratory flow was also measured.
Skin prick test responses with carnation extract were positive in 15 of the 16 patients and negative in all control subjects.
Nasal provocation test responses with carnation extract were positive in 13 of 16 patients.
A significant correlation was seen between RAST and nasal provocation results (P<. 01). (...)
Mots-clés Pascal : Asthme, Allergie, Rhinite, Etiologie, Allergène, Dianthus caryophyllus, Caryophyllaceae, Dicotyledones, Angiospermae, Spermatophyta, Fleur, Horticulture, Exposition professionnelle, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Immunopathologie, Médecine travail, ORL pathologie, Nez pathologie
Mots-clés Pascal anglais : Asthma, Allergy, Rhinitis, Etiology, Allergen, Dianthus caryophyllus, Caryophyllaceae, Dicotyledones, Angiospermae, Spermatophyta, Flower, Horticulture, Occupational exposure, Human, Respiratory disease, Obstructive pulmonary disease, Immunopathology, Occupational medicine, ENT disease, Nose disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0410847
Code Inist : 002B06C02. Création : 22/03/2000.