Aims-To estimate the incidence of corneal melting or necrotising keratitis in association with systemic disease in the Yorkshire Region and to determine the type and duration of the systemic association.
Methods-In a prospective study, vigorous attempts were made to identify all patients presenting with newly diagnosed corneal melting over a 3 year period.
27 patients were identified during the study period.
Rheumatoid arthritis and Wegener's granulomatosis were the most common disease associations.
Corneal melting was a late complication of rheumatoid arthritis, but usually occurred during early and overt systemic disease in patients with Wegener's granulomatosis.
Conclusion-The annual incidence of corneal melting in the Yorkshire Region is 3.01/million/year (95% CI=0.7-9.6).
Mots-clés Pascal : Kératite, Nécrose, Cornée, Maladie système, Association, Incidence, Prospective, Royaume Uni, Europe, Homme, Oeil pathologie, Kératopathie, Immunopathologie
Mots-clés Pascal anglais : Keratitis, Necrosis, Cornea, Systemic disease, Association, Incidence, Prospective, United Kingdom, Europe, Human, Eye disease, Keratopathy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0408921
Code Inist : 002B07. Création : 22/03/2000.