Background The incidence of contact-lens-associated microbial keratitis is uncertain and its related morbidity in the general population of contact-lens wearers is not known.
We examined these issues in a prospective epidemiological study.
Methods We surveyed all practising ophthalmologists in the Netherlands to identify all new cases of microbial keratitis reported during a 3-month period in 1996.
Follow-up telephone calls were made to examine ocular morbidity.
We undertook annual nationwide telephone surveys between 1994 and 1997 to estimate the prevalence of contact-lens wear.
Findings Of 440 ophthalmologists contacted, 379 provided information.
There were 92 cases of microbial keratitis ; 17 used daily-wear rigid gas-permeable lenses, 63 daily-wear soft lenses, and 12 extended-wear soft lenses.
The estimated annualised incidence of microbial keratitis was 1.1 per 10 000 (95% Cl 0.6-1.7) users of daily-wear rigid gas-permeable lenses, 3.5 per 10 000 (2.7-4.5) users of daily-wear soft lenses, and 20.0 per 10 000 (10.3-35.0) users of extended-wear soft lenses (p<0.00001 for comparison between all groups), Five of the 92 patients achieved a final visual acuity of 20/70 or less.
Pseudomonas and Serratia spp were the organisms most commonly isolated.
Pseudomonas keratitis accounted for the largest mean diameter of corneal ulcers, the highest mean number of days in hospital, the greatest number of mean outpatients visits, and the poorest visual acuity outcome. (...)
Mots-clés Pascal : Kératite, Lentille cornéenne, Morbidité, Pays Bas, Europe, Facteur risque, Incidence, Epidémiologie, Complication, Homme, Oeil pathologie, Kératopathie, Bactériose, Infection
Mots-clés Pascal anglais : Keratitis, Contact lens, Morbidity, Netherlands, Europe, Risk factor, Incidence, Epidemiology, Complication, Human, Eye disease, Keratopathy, Bacteriosis, Infection
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0404520
Code Inist : 002B05B02A. Création : 22/03/2000.