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  1. Mortality in young adults in England and Wales : the impact of the HIV epidemic.

    Article - En anglais

    Objective 

    To quantify the contribution of the HIV epidemic to premature mortality in England and Wales 1985-1996.

    Design 

    Surveillance of deaths in HIV-infected individuals and causes of death from death certificates.

    Main outcome measures 

    Time trends in age-specific mortality rates among 15-44 year olds and years of potential life lost (YPLL) to age 65 associated with HIV infection and other important causes of death in young adults.

    Results 

    The crude age-specific mortality rates for all causes of death in the 15-44 year age band remained fairly constant between 1985 and 1996 : in other age bands a decrease was seen.

    Deaths from both suicide and HIV increased in men aged 15-44 years.

    Although suicide accounted for a greater number of deaths throughout the period investigated, the largest proportional and absolute increase was seen for deaths in HIV-infected people.

    By 1996, the contribution of HIV to YPLL to age 65 varied from less than 0.5% in most rural localities to 20% of total YPLL in one London health authority.

    Conclusions 

    While part of the adverse trend in mortality in younger adults since 1985 was attributable to suicide, most resulted from HIV infection.

    The impact of HIV infection on mortality was greatest in London.

    Mots-clés Pascal : SIDA, Virose, Infection, Mortalité, Epidémiologie, Adulte jeune, Homme, Etiologie, Pays de Galles, Grande Bretagne, Royaume Uni, Europe, Angleterre, Surveillance sanitaire, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Mortality, Epidemiology, Young adult, Human, Etiology, Wales, Great Britain, United Kingdom, Europe, England, Sanitary surveillance, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0404195

    Code Inist : 002B30A01A2. Création : 22/03/2000.