The recent licensing of active hepatitis A vaccines raises the question of vaccine candidates.
Although various groups of workers are at theoretical occupational risk of hepatitis A infection, no comprehensive quantitative data exist to determine which occupational groups should receive active vaccination.
Therefore, the aims of this study were to identify occupations at risk for hepatitis A infection and to determine their relative risk.
In this nationwide historical prospective study, the relative risk of hepatitis A among different occupations in Israel was determined according to the incidence of hepatitis A in different occupations during 1993 and 1994 compared with the incidence of hepatitis A in two standard populations.
After age, gender, ethnicity, and time of immigration to Israel were controlled for, certain occupations showed a significant increased risk of hepatitis A : yeshiva students (standardized incidence ratio (SIR)=9.98,99% confidence interval : 7.55,13.18), day care center and kindergarten staff (SIR=5.47,99% confidence interval : 3.50,8.57), food industry workers (SIR=5.41,99% confidence interval : 1.92,15.25), teachers (SIR=4.02,99% confidence interval : 2.92,5.48), physicians and dentists (SIR=3.77,99% confidence interval : 1.78,8.14), and therapists and medical technicians (SIR=3.75,99% confidence interval : 1.75,8.14).
Sewage workers and nurses did not show any significantly increased risk. (...)
Mots-clés Pascal : Hépatite virale A, Virose, Infection, Homme, Milieu professionnel, Statut professionnel, Facteur risque, Prévention, Vaccination, Etude longitudinale, Israël, Asie, Epidémiologie, Incidence, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis A, Viral disease, Infection, Human, Occupational environment, Professional status, Risk factor, Prevention, Vaccination, Follow up study, Israel, Asia, Epidemiology, Incidence, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0403294
Code Inist : 002B05C02G. Création : 22/03/2000.