The proverbial relative risk may not always be the most suitable measure to compare the risk of two exposures, since it inherently includes a background effect.
An alternative comparative measure, the relative excess risk, is introduced.
It applies to situations in which an « unexposed » reference group is included in addition to the two exposures under evaluation.
This comparative measure is based solely on the component of risk due to the exposures, since it removes the background risk.
Estimators of the relative excess risk are presented, along with formulas for the confidence intervals under cohort and case-control designs, using both crude and adjusted rate ratios.
This new measure is illustrated with data from epidemiologic studies of the risks of oral contraceptives and antidiabetic drugs.
Mots-clés Pascal : Canada, Amérique du Nord, Amérique, Epidémiologie, Méthodologie, Homme, Santé, Evaluation, Risque, Exposition, Etude comparative, Etude cohorte, Etude cas témoin, Statistique
Mots-clés Pascal anglais : Canada, North America, America, Epidemiology, Methodology, Human, Health, Evaluation, Risk, Exposure, Comparative study, Cohort study, Case control study, Statistics
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0403183
Code Inist : 002B30A01A1. Création : 22/03/2000.