The risk of human immunodeficiency virus (HIV) transmission from various types of homosexual contact, including oral sex, is of biologic, epidemiologic, and public health importance.
The per-contact risk of acquiring HIV infection from specific acts was estimated in a prospective cohort study of 2,189 high-risk homosexual and bisexual men, conducted in San Francisco, California ; Denver, Colorado ; and Chicago, Illinois, in 1992-1994.
During 2,633 person-years of follow-up, 60 seroconversions were observed.
The estimated per-contact risk of acquiring HIV from unprotected receptive anal intercourse (URA) was 0.82 percent (95% confidence interval : 0.24,2.76 percent) when the partner was known to be HIV+and 0.27 percent (95% confidence interval : 0.06,0.49 percent) when partners of unknown serostatus were included.
There was heterogeneity in per-contact risk, with nine seroconversions occurring after only one or two episodes of URA.
The per-contact risk associated with unprotected insertive anal and receptive oral sex with HIV-positive or unknown serostatus partners was 0.06 and 0.04 percent, respectively.
URA accounted for only 15 percent of all reported sexual activity by seroconverters.
As lower-risk practices become more common, they may play a larger role in propagating the epidemic and should also be addressed by interventions targeting high-risk homosexual and bisexual men.
Mots-clés Pascal : SIDA, Virose, Infection, Homme, Facteur risque, Transmission homme homme, Homosexualité, Mâle, Comportement sexuel, Bisexualité, Etude cohorte, Etude multicentrique, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Incidence, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Human, Risk factor, Transmission from man to man, Homosexuality, Male, Sexual behavior, Bisexuality, Cohort study, Multicenter study, United States, North America, America, Epidemiology, Incidence, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0403080
Code Inist : 002B05C02D. Création : 22/03/2000.