We aimed to study the prevalence patterns and course of benzodiazepine (BZD) abuse in an Israeli methadone maintenance (MMT) clinic using repeated random observed urine analysis as well as self-report data.
Lifetime and current prevalence of BZD abuse were found in 66.3 and 50.8% patients, respectively.
It was found that 44.6% of patients who abused BZDs during their first month of treatment ceased to do so after I year, while 27.4% who had not abused BZDs at the beginning of MMT did so after 1 year in treatment.
Flunitrazepam was the most commonly abused BZD (92.9%), followed by diazepam (54.3%) and oxazepam (38.6%). Most of the patients swallowed BZDs (92.8%), 42.9% also smoked or snorted them while 8.6% injected BZDs intravenously.
BZDs were used as self-medication for alleviating emotional problems rather than for recreational or other reasons.
We conclude that BZD abuse is a significant clinical problem in heroin addicts both before entering and during MMT.
MMT may have a positive as well as a negative influence on BZD abuse with the former being more prevalent.
Mots-clés Pascal : Toxicomanie, Traitement substitutif, Sevrage toxique, Méthadone, Analgésique narcotique, Facteur risque, Abus, Benzodiazépine dérivé, Psychotrope, Epidémiologie, Israël, Asie, Homme, Opiacés
Mots-clés Pascal anglais : Drug addiction, Replacement therapy, Detoxification, Methadone, Narcotic analgesic, Risk factor, Abuse, Benzodiazepine derivatives, Psychotropic, Epidemiology, Israel, Asia, Human, Opiates
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0402340
Code Inist : 002B18I15. Création : 22/03/2000.