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  1. Second primary cancers in patients with lung carcinoma.

    Article - En anglais


    There are only limited population-based data available regarding the risk of developing a second cancer after a diagnosis of lung carcinoma.


    Data collected from the Cancer Registry of the Swiss Canton of Vaud (comprised of approximately 600,000 inhabitants) were used to estimate the incidence of a second metachronous primary cancer following a diagnosis of lung carcinoma.

    Between 1974 and 1996,5794 cases of lung carcinoma (occurring in 4728 males and 1066 females) were followed actively until the end of 1996.


    One hundred seventy-five second primary neoplasms were registered (occurring in 146 males and 29 females).

    Significant excess rates were observed for all cancer sites (standardized incidence ratio [SIR]=1.2), cancers of the oral cavity and pharynx (SIR=2.7), and lung (SIR=1.7).

    SIRs also were above unity for cancers of the esophagus (SIR=1.8), pancreas (SIR=1.5), bladder (SIR=1.8), kidney (SIR=2.3), and the female breast (SIR=2.0).

    Excess rates for all cancer sites together and tobacco-related neoplasms were systematically higher at a younger age (<60 years).

    The overall cumulative risk of lung cancer was 1.8% at 5 years and 4.7% at 10 years and was 5% and 11%, respectively, for any tobacco-related tumor.

    The estimates were consistent for squamous cell carcinoma and adenocarcinoma of the lung. (...)

    Mots-clés Pascal : Carcinome, Bronchopulmonaire, Second cancer, Incidence, Epidémiologie, Registre, Suisse, Europe, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Tumeur maligne

    Mots-clés Pascal anglais : Carcinoma, Bronchopulmonary, Second cancer, Incidence, Epidemiology, Register, Switzerland, Europe, Human, Respiratory disease, Lung disease, Bronchus disease, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0373350

    Code Inist : 002B11A. Création : 22/03/2000.