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  1. A method for identifying abrupt changes in U.S. cancer mortality trends.

    Article - En anglais


    Summaries of trends in cancer rates evaluated over a fixed, short period are informative, but methods that evaluate trends over a longer time period, identifying when changes occur as well as the magnitude of the changes, can provide additional information.


    Cancer mortality trends from 1973-1995 were determined for more than 15 anatomic sites for white and black males and females using weighted piecewise linear regression analysis with a stepwise selection procedure.

    The dependent variable was the natural logarithm of the annual mortality rate, and the weight was the annual number of cancer deaths.

    The variability of estimated change points

    was examined by bootstrapping the residuals from the resulting models.


    For black males, cancer mortality rates declined in the 1990s due to decreases in lung, esophageal, oral cavity, and prostate cancer rates.

    However, there was no significant decline for cancer of the colon and rectum.

    For white males, cancer mortality rates declined in the 1990s due to declines in cancer of the lung and colon/rectum since the mid-1980s and declines in prostate cancer in the 1990s.

    For black females and white females, total cancer mortality rates declined, but not significantly.

    Cancer rates for all sites except the lung declined significantly in the 1990s for white, but not black, females due to declining trends for carcinoma of the colon and rectum since the mid-1980s and for breast cancer in the 1990s. (...)

    Mots-clés Pascal : Tumeur maligne, Hémopathie maligne, Mortalité, Epidémiologie, Modèle régression, Régression linéaire, Analyse statistique, Etats Unis, Amérique du Nord, Amérique, Homme

    Mots-clés Pascal anglais : Malignant tumor, Malignant hemopathy, Mortality, Epidemiology, Regression model, Linear regression, Statistical analysis, United States, North America, America, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0369547

    Code Inist : 002B04B. Création : 14/12/1999.