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  1. Risk of transmission of bovine spongiform encephalopathy to humans in the United States : Report of the council on scientific affairs.

    Article - En anglais

    Context The risk of possible transmission of bovine spongiform encephalopathy (BSE) in the United States is a substantial public health concern.

    Objective To systematically review the current scientific literature and discuss legislation and regulations that have been implemented to prevent the disease.

    Methods Literature review using the MEDLINE, EMBASE, and Lexis/Nexis databases for 1975 through 1997 on the terms bovine spongiform encephalopathy, prion diseases, prions, and Creutzfeldt-Jakob syndrome.

    The Internet was used to identify regulatory actions and health surveillance.

    Data Extraction MEDLINE, EMBASE, and Lexis/Nexis databases were searched from 1975 through 1997 for English-language articles that provided information on assessment of transmission risk.

    Results Unique circumstances in the United Kingdom caused the emergence and propagation of BSE in cattle, including widespread use of meat and bonemeal cattle feed derived from scrapie-infected sheep and the adoption of a new type of processing that did not reduce the amount of infectious prions prior to feeding.

    Many of these circumstances do not exist in the United States.

    In the United Kingdom, new variant Creutzfeldt-Jakob disease probably resulted from the ingestion of BSE-contaminated processed beef.

    The United Kingdom and the European Union now have strong regulations in place to stop the spread of BSE. (...)

    Mots-clés Pascal : Encéphalopathie spongiforme, Bovin, Artiodactyla, Ungulata, Mammalia, Vertebrata, Facteur risque, Transmission animal homme, Revue bibliographique, Base donnée bibliographique, Forme clinique, Epidémiologie, Prévention, Compte rendu, Homme, Etats Unis, Amérique du Nord, Amérique, Prion, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative

    Mots-clés Pascal anglais : Spongiform encephalopathy, Bovine, Artiodactyla, Ungulata, Mammalia, Vertebrata, Risk factor, Transmission from animal to man, Bibliographic review, Bibliographical batabase, Clinical form, Epidemiology, Prevention, Report, Human, United States, North America, America, Prion, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0365355

    Code Inist : 002B17G. Création : 14/12/1999.