Opioids are our most powerful analgesics, but politics, prejudice, and our continuing ignorance still impede optimum prescribing.
Just over 100 years ago, opium poppies were still grown on the Cambridgeshire fens In the UK to provide oblivion for the working man and his family, but the brewing lobby argued on thin evidence that their potions were less dangerous.
The restriction of opioid avallability to protect society and the individual continues In many countries.
In this review I focus on chronic and cancer pain, but many of the principles apply in acute pain.
The justification for this focus is that patients with chronic pain may suffer longer and unnecessarily If we prescribe and legislate badly.
Mots-clés Pascal : Douleur, Gestion, Protocole thérapeutique, Peptide opioïde, Pharmacocinétique, Choix substrat, Aspect médicolégal, Voie administration, Tolérance, Efficacité traitement, Article synthèse, Indication, Homme, Royaume Uni, Europe, Système nerveux central pathologie, Système nerveux pathologie, Opiacés
Mots-clés Pascal anglais : Pain, Management, Therapeutic protocol, Opioid peptide, Pharmacokinetics, Substrate selection, Forensic aspect, Route of administration, Tolerance, Treatment efficiency, Review, Indication, Human, United Kingdom, Europe, Central nervous system disease, Nervous system diseases, Opiates
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0365343
Code Inist : 002B02B09F. Création : 14/12/1999.