The risk factors for the development of heart failure are not clearly defined, particularly for older adults.
We undertook the current investigation to examine the associations of traditional cardiovascular risk factors, comorbidity, and psychosocial factors with the risk of heart failure during 10 years of follow-up in a community-based elderly population.
We evaluated 1,749 subjects, 65 years ofage or older, free of heart failure, myocardial infarction, and angina at baseline, who were participating in the New Haven, Connecticut cohort of the Established Population for Epidemiologic Studies of the Elderly program.
Cox proportional hazards regression models were used to determine risk ratios (RR) and 95% confidence intervals (CI).
During 13,811 person-years of follow-up, 173 subjects developed incident heart failure, as confirmed by chart review.
Five factors were independent predictors of heart failure : male sex (RR=1.7 ; CI, 1.3 to 2.4), older age (RR=1.9 ; CI, 1.3 to 2.7 for age 75 to 84 years, RR=3.0 ; CI, 1.7 to 5.5 for age 85 years and older, compared with <=74 years), diabetes (RR=2.9 ; Cl, 2.0 to 4.3), pulse pressure >=70 mm Hg (RR=2.3 ; CI, 1.3 to 4.3, compared with<50 mm Hg), and body mass index >=28 kg/m2 (RR=1.6 ; CI, 1.0 to 2.4, compared with<24 kg/m2).
Myocardial infarction occurred during follow-up in 8% of the cohort and was also an important predictor of heart failure (RR=21 ; CI, 15 to 31). (...)
Mots-clés Pascal : Insuffisance cardiaque, Facteur risque, Age, Incidence, Association morbide, Epidémiologie, Personne âgée, Homme, Appareil circulatoire pathologie, Cardiopathie
Mots-clés Pascal anglais : Heart failure, Risk factor, Age, Incidence, Concomitant disease, Epidemiology, Elderly, Human, Cardiovascular disease, Heart disease
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0355609
Code Inist : 002B12A01. Création : 14/12/1999.