Globally, the proportion of all cases of tuberculosis (TB) caused by drug-resistant strains is increasing.
We report the case of a Canadian citizen who acquired a highly drug-resistant strain of Mycobacterium bovis while visiting a relative with AIDS-related tuberculosis in Spain.
The origin of the strain was traced using spoligotyping, a polymerase chain reaction (PCR) - based fingerprint technology, and the European DNA database.
The level of primary drug resistance-all five first-line drugs and 19 of 21 second-line drugs-in this case was unprecedented in Canada.
Isolation of this strain from a Canadian citizen represents the first report of its appearance in this hemisphere.
The infection was contained and combined medical-surgical treatment delivered.
Mots-clés Pascal : Tuberculose, Mycobactériose, Bactériose, Infection, Poumon, Résistance traitement, Contamination, Transmission homme homme, Monde, Etude cas, Homme, Appareil respiratoire pathologie, Poumon pathologie
Mots-clés Pascal anglais : Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Lung, Negative therapeutic reaction, Contamination, Transmission from man to man, World, Case study, Human, Respiratory disease, Lung disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0353246
Code Inist : 002B05B02O. Création : 14/12/1999.