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  1. Evaluation of the effectiveness of vaccination against diphtheria among medical staff of the chair and the Jagiellonian University Hospital of Infectious Diseases in Cracow, Poland. Some epidemiological observations.

    Article - En anglais

    In Poland, twenty-five cases of diphtheria, mostly among adults (including five foreigners) in the region adjacent to the eastern border were registered in the years 1992-1996.

    In 1993-1994, because of the threat of diphtheria infection, 41 healthy members of the medical staff of the University Hospital of Infectious Diseases in Krak6w, mainly women aged 25-57 years were immunized with Td and d vaccines with a 6-month interval between courses.

    Prior to vaccination, 17 (41%) individuals showed a lack of diphtheria antibodies as determined with a passive haemagglutination test. 14 of them were aged 30-49 years.

    Six months after the 2nd dose of vaccine, all seronegative persons had developed a protective level of antibodies.

    Moreover, all vaccinated subjects showed a statistically significant increase of the antibody titre between the first and last serological examinations.

    Mots-clés Pascal : Corynebacterium diphtheriae, Corynebacteriaceae, Actinomycetes, Bactérie, Homme, Diphtérie, Bactériose, Infection, Vaccination, Personnel sanitaire, Milieu hospitalier, Prévention, Immunoprotection, Epidémiologie, Prévalence, Pologne, Europe

    Mots-clés Pascal anglais : Corynebacterium diphtheriae, Corynebacteriaceae, Actinomycetes, Bacteria, Human, Diphtheria, Bacteriosis, Infection, Vaccination, Health staff, Hospital environment, Prevention, Immunoprotection, Epidemiology, Prevalence, Poland, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0351200

    Code Inist : 002B05B02A. Création : 14/12/1999.