With few exceptions (e.g., Lesch-Nyhan syndrome), the specific nature of self-injury in relation to identified genetic syndromes associated with mental retardation is poorly understood.
In the present study we surveyed the families of 62 persons with Prader-Willi syndrome to determine the prevalence, topographies, and specific body locations of self-injurious behavior.
Self-injury was reported for 81% of the participants.
Skin-picking was the most prevalent form, with the front of the legs and head being disproportionately targeted as preferred self-injury body sites.
Individuals with the 15q11-q13 deletion injured significantly more body sites than did individuals with maternal disomy 15.
Results are discussed in relation to previous self-injury body site findings and implications for the relevance of syndrome-specific behavioral phenotypes.
Mots-clés Pascal : Automutilation, Arriération mentale, Prader Labhart Willi syndrome, Prévalence, Epidémiologie, Symptomatologie, Homme, Déficience intellectuelle, Trouble développement, Endocrinopathie, Système ostéoarticulaire pathologie, Maladie héréditaire, Syndrome complexe
Mots-clés Pascal anglais : Self injury, Mental retardation, Prader Labhart Willi syndrome, Prevalence, Epidemiology, Symptomatology, Human, Intellectual deficiency, Developmental disorder, Endocrinopathy, Diseases of the osteoarticular system, Genetic disease, Complex syndrome
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0351037
Code Inist : 002B18C12. Création : 14/12/1999.