The objective of this study was to identify risk factors for sudden cardiac arrest (SCA) in patients with coronary artery disease (CAD).
A retrospective case-control study was performed consisting of a group of unselected patients who had suffered SCA and had a clinical history of CAD, and a group of unselected age-and gender-matched CAD control patients living in the region of Maastricht.
Information about previous myocardial infarction (MI), left ventricular ejection fraction (LVEF), hypertension, hypercholesterolemia, diabetes mellitus, smoking, and coffee and alcohol consumption was collected.
A logistic regression model was fitted to all mentioned variables including age and genders.
Included were 117 SCA cases (84% men, mean age 65 years [± 7]) and 144 control patients (83% men, mean age 63 years [±8]). Previous MI (odds ratio [OR] 4.0,95% confidence interval [CI] 1.7-9.3), hypertension (OR 2.9,95% CI 1.5-6.1), heavy coffee consumption (>10 cups per day) (OR 55.7,95% Cl 6.4-483), and a LVEF<40% (OR 11.2, Cl 4.4-28.5) were independent risk indicators for SCA in patients with CAD.
Alcohol consumption (1-21 glasses per week) seemed to protect patients with CAD from SCA (OR 0.5,95% CI 0.2-0.98).
These observations suggest that changes in lifestyle factors can be of potential importance in protecting patients with CAD from dying suddenly.
Mots-clés Pascal : Arrêt cardiocirculatoire, Mort subite, Cardiopathie coronaire, Café, Consommation, Boisson alcoolisée, Ethanol, Mode de vie, Epidémiologie, Facteur risque, Homme, Pays Bas, Europe, Etude cas témoin, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Cardiocirculatory arrest, Sudden death, Coronary heart disease, Coffee, Consumption, Alcoholic beverage, Ethanol, Life style, Epidemiology, Risk factor, Human, Netherlands, Europe, Case control study, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0350942
Code Inist : 002B12A03. Création : 14/12/1999.