To test the hypothesis that osteoporosis, which results partly from long-term estrogen deficiency, is associated with a lowered risk of breast cancer, a population-based cohort study was performed in Amiens.
To ascertain the incidence of breast cancer, 1300 women were followed through after a first hip fracture.
Overall, 18 cases of cancer were observed cf. 21.8 expected (standardized incidence ratio (SIR) : 0.82 ; 95% confidence interval (CI) : 0.5-1.3).
The results are consistent with previous studies which concluded that long-term estrogen deficiency is associated with a reduced risk of developing breast cancer.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Fracture, Hanche, Ostéoporose, Oestrogène, Epidémiologie, Facteur risque, Incidence, Homme, Femelle, Prévention, France, Europe, Glande mammaire pathologie, Système ostéoarticulaire pathologie, Traumatisme, Ostéopathie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Fracture, Hip, Osteoporosis, Estrogen, Epidemiology, Risk factor, Incidence, Human, Female, Prevention, France, Europe, Mammary gland diseases, Diseases of the osteoarticular system, Trauma, Bone disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0349517
Code Inist : 002B20E02. Création : 14/12/1999.