Alcohol and stroke : A community case-control study in Asturias, Spain.
The relationship between alcohol consumption and stroke is uncertain.
Heavy alcohol consumption has been associated with an increased risk of stroke, while light drinking appears to be protective.
However, the evidence is not uniform.
We sought to examine the relationship between alcohol consumption and stroke, according to stroke type.
We performed a population-based case-control study from September 1990 to December 1991.
The study comprised 467 incident cases of stroke and 477 controls aged between 40 and 85.
Case was defined following WHO criteria and control was randomly selected from the study base population.
Alcohol exposure was obtained by medical interview.
We found that consumption of less than 30 g./day of alcohol was protective against all stroke types combined, the multivariated adjusted odds ratio (OR) was 0.58 (95% confidence interval [CI], 0.41-0.83).
Moderate alcohol drinking is also protective against all cerebral infarction combined (OR=0.53 ; 95% Cl, 0.35-0.80) and cortical infarction (OR=0.40 ; 95% Cl, 0.18-0.86).
Drinking up to 30 g/day of alcohol has a borderline protective effect on deep cerebral infarction (OR=0.40 ; 95% Cl, 0.16-1.02) and has no effect on intracerebral hemorrhage (OR=0.88 ; 95% CI, 0.44-1.74).
Heavy alcohol drinking, over 140 g/day, is a risk factor for all stroke types combined (OR=3.2 ; 95% CI, 1.1-9.7), all cerebral infarction combined (OR=5.0 ; 95% CI, 1.5-16.3), small deep cerebral infarction (OR=9.7 ; 95% Cl, 2.6-36. (...)
Mots-clés Pascal : Accident cérébrovasculaire, Consommation, Boisson alcoolisée, Ethanol, Epidémiologie, Facteur risque, Homme, Espagne, Europe, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie
Mots-clés Pascal anglais : Stroke, Consumption, Alcoholic beverage, Ethanol, Epidemiology, Risk factor, Human, Spain, Europe, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0349378
Code Inist : 002B17C. Création : 14/12/1999.