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  1. Survival after rectal cancer : differences between hospital catchment areas. A nationwide study in Sweden.

    Article - En anglais

    Background-The quality of rectal cancer surgery at small units has been debated.

    No national studies of this issue have been undertaken and most studies have been based on insufficient data to clarify the controversy.

    It has been claimed that observed differences in outcomes between specialised centres and smaller hospitals are confounded by differences in stage/severity.

    Aim-To compare survival after rectal cancer between hospital catchment areas.

    Patients-All patients with rectal cancer notified to the Swedish Cancer Register in 1973-1992 (n=30 811) were followed up by record linkage to the nationwide Death Register.

    Methods-Relative survival-that is, ratio of observed to expected survival-was computed as a measure of excess mortality attributable to rectal cancer.

    Multivariate analysis was then performed to estimate the independent effects of hospital catchment area categories and age, year of diagnosis, and duration of follow up.


    One year relative survival among rectal cancer patients residing in catchment areas of large regional hospitals was 76%, compared with 72% for small local hospitals (p<0.001).

    A difference was already noted after 30 days and remained five years after diagnosis.

    Relative survival improved considerably overall, but the differences between catchment area categories persisted.

    These were not reduced by adjustment for age, time after diagnosis, or time period in multivariate models. (...)

    Mots-clés Pascal : Carcinome, Rectum, Traitement, Proctocolectomie, Evolution, Survie, Répartition géographique, Variabilité, Epidémiologie, Homme, Suède, Europe, Côlon, Tumeur maligne, Appareil digestif pathologie, Intestin pathologie, Rectum pathologie, Chirurgie

    Mots-clés Pascal anglais : Carcinoma, Rectum, Treatment, Proctocolectomy, Evolution, Survival, Geographic distribution, Variability, Epidemiology, Human, Sweden, Europe, Colon, Malignant tumor, Digestive diseases, Intestinal disease, Rectal disease, Surgery

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0346358

    Code Inist : 002B13B01. Création : 14/12/1999.