To determine prospectively the etiology, pattern of infection, antibiotic sensitivity of pathogens and the outcome of the infection.
Patients with any of the clinical manifestations of septicemia such as feeding intolerance, lethargy, apnoeic spells, cyanotic spells, vomiting, hypothermia and hyperthermia, and positive blood cultures were admitted into the study in the Neonatal Intensive Care Unit of King Saud Hospital, Unayzah, Al Gassim - one of the 2 referral Hospitals in the region.
The study was carried out over a 12 month period from August 1995 to July 1996.
There were 2,620 deliveries out of which 324 (12%) were admitted into the Neonatal Intensive Care Unit with varying problems during this period of study.
Thirty-four (10.5%) (21 males and 13 females) of those admitted had septicemia.
There were 24 preterm babies and 10 term babies.
Eleven out of the 24 preterm (46%) and also 2 out of the 10 term babies (20%) died.
The overall case mortality was 38% (13/34).
There were more deaths in males than females - 61.5% and 38.5%, a ratio of 1.6 : 1. Sixty five percent of the total isolates were gram negative and 35% gram positives.
The 4 most common isolates were pseudomonas, E. Coli, Coagulase negative staphylococcus, and Group B streptococcus, which constituted 76.5% of all the isolates and contributed to 77% of all mortality. (...)
Mots-clés Pascal : Septicémie, Néonatal, Etiologie, Pronostic, Arabie Saoudite, Asie, Incidence, Mortalité, Nouveau né, Homme, Epidémiologie
Mots-clés Pascal anglais : Septicemia, Neonatal, Etiology, Prognosis, Saudi Arabia, Asia, Incidence, Mortality, Newborn, Human, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0346019
Code Inist : 002B05B02M. Création : 14/12/1999.