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  1. Determination of factors responsible for the declining incidence of colorectal cancer.

    Article, Communication - En anglais

    World Congress of Gastroenterology. Vienna, ATR, 1998/09/09.

    INTODUCTION : After rising for 13 years in the United States, the incidence of colorectal cancer began to fall in 1986 and has continued to drop since then.

    This report contains an analysis of the pattern of declining colorectal cancer risk by colorectal subsite, race, and gender and a time trend investigation of suspected risk modifiers of colorectal cancer.


    Colorectal cancer incidence data were obtained from the Surveillance, Epidemiology, and End Results Public Use Files from 1973 to 1994.

    The following exposure variables were assessed, focussing principally on the period 1970 to 1980 : dietary fat, fiber, ethanolic beverages, vitamin A, vitamin C, iron, calcium, estrogen, aspirin, energy intake, body mass index, serum cholesterol, body iron stores, cholecystectomy, constipation, cigarette use, physical activity, and colonoscopic polypectomy.

    Data sources used in these analyses were principally National Health and Nutrition Examination Surveys I, II, and III.


    After 1985 colorectal cancer incidence declined predominantly in the distal colorectum almost equally in both white males and white females.

    Some exposures remained unchanged or trended in the wrong direction (dietary fat, calcium, ethanol, energy intake, physical activity, overweight prevalence, and cholecystectomy).

    Others did not apply equally to both genders (estrogen, aspirin, ethanol, calcium, and cholecystectomy). (...)

    Mots-clés Pascal : Carcinome, Côlon, Rectum, Evolution, Diminution, Incidence, Colonoscopie, Dépistage, Résection chirurgicale, Epidémiologie, Homme, Tumeur maligne, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie, Endoscopie, Chirurgie endoscopique

    Mots-clés Pascal anglais : Carcinoma, Colon, Rectum, Evolution, Decrease, Incidence, Colonoscopy, Medical screening, Surgical resection, Epidemiology, Human, Malignant tumor, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease, Endoscopy, Endoscopic surgery

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0345833

    Code Inist : 002B30A01C. Création : 14/12/1999.