The U.K. human fertilisation and embryology authority : How it has contributed to the evaluation of assisted reproduction technology : Assessing reproductive technology.
The Human Fertilisation and Embryology Act of the United Kingdom was passed in 1990, leading to the formation of the Human Fertilisation and Embryology Authority (HFEA), the first statutory body to regulate and control assisted conception anywhere in the world.
The principal function of the HFEA is to license and monitor clinics that carry out in vitro fertilization (IVF), donor insemination (DI), and embryo research.
Information on over 135,000 treatment cycles, 20,000 pregnancies, and 25,000 babies following IVF has now been collected as part of the regulatory process, and these data have permitted unbiased and accurate evaluation of treatment efficacy using pregnancy and live-birth rates.
The treating clinics are required by law to provide information on the outcome of all births, including neonatal mortality and congenital malformations, but there is no systematic validation of these data using medical records or any follow-up of treated women, or babies, over time.
In addition, the strict confidentiality of data supplied to the HFEA means that outside researchers have been unable to access the database for research projects.
Thus, at the present time, it is not possible to evaluate the long-term safety of assisted conception procedures using HFEA data.
There is reasonable scientific evidence to justify full investigation of the health of both treated women and resulting children. (...)
Mots-clés Pascal : Fécondation in vitro transfert embryon, Royaume Uni, Europe, Homme, Femelle, Ethique, Législation, Autorité, Organisation, Surveillance, Recherche scientifique, Médecine, Politique sanitaire, Expérimentation, Embryon, Article synthèse, Technologie, Procréation assistée
Mots-clés Pascal anglais : In vitro fertilization embryo transfer, United Kingdom, Europe, Human, Female, Ethics, Legislation, Authority, Organization, Surveillance, Scientific research, Medicine, Health policy, Experimentation, Embryo, Review, Technology, Assisted procreation
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0342944
Code Inist : 002B31. Création : 14/12/1999.