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  1. Polymyalgia rheumatica with low erythrocyte sedimentation rate at diagnosis.

    Article - En anglais


    To determine the frequency and clinical characteristics of polymyalgia rheumatica (PMR) with low erythrocyte sedimentation rate (ESR) at diagnosis in a community based cohort of 232 patients.


    A retrospective review of medical records of all the patients with a diagnosis of PMR in Olmsted County, Minnesota, seen and followed over a 22 year period, from 1970 through 1991.


    Seventeen (7.3%) patients had ESR<40 mm/h at diagnosis.

    The findings and outcome in these patients were compared with the others in the group.

    There was no difference in sex or age between the 2 groups.

    Both groups had the same delay to diagnosis, typical gradual onset of the disease, the same frequency of both proximal and distal stiffness/pain, and the same frequency of synovitis.

    Systemic features were less frequent in the low ESR group than in the high ESR group (59 vs 81%, p=0.05).

    Mean ESR in the low ESR group was 26 ± 9 mm/h versus 74 ± 24 mm/h in the high ESR group.

    The mean hemoglobin concentration was significantly lower (p=0.0015) in the high compared to the low ESR group (12.2 ± 1.4 g/dl versus 13.3 ± 1.3 g/dl).

    The frequency of positive temporal artery biopsy and of diagnosed giant cell arteritis was the same in the 2 groups.

    Initial response to therapy, frequency of relapses, number of patients going into remission, time to remission, and daily dose of steroids were the same in both groups. (...)

    Mots-clés Pascal : Pseudopolyarthrite rhizomélique, Diagnostic, Vitesse sédimentation, Epidémiologie, Fréquence, Symptomatologie, Pronostic, Personne âgée, Homme, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire

    Mots-clés Pascal anglais : Polymyalgia rheumatica, Diagnosis, Sedimentation rate, Epidemiology, Frequency, Symptomatology, Prognosis, Elderly, Human, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0342231

    Code Inist : 002B15D. Création : 14/12/1999.