To determine the frequency and clinical characteristics of polymyalgia rheumatica (PMR) with low erythrocyte sedimentation rate (ESR) at diagnosis in a community based cohort of 232 patients.
A retrospective review of medical records of all the patients with a diagnosis of PMR in Olmsted County, Minnesota, seen and followed over a 22 year period, from 1970 through 1991.
Seventeen (7.3%) patients had ESR<40 mm/h at diagnosis.
The findings and outcome in these patients were compared with the others in the group.
There was no difference in sex or age between the 2 groups.
Both groups had the same delay to diagnosis, typical gradual onset of the disease, the same frequency of both proximal and distal stiffness/pain, and the same frequency of synovitis.
Systemic features were less frequent in the low ESR group than in the high ESR group (59 vs 81%, p=0.05).
Mean ESR in the low ESR group was 26 ± 9 mm/h versus 74 ± 24 mm/h in the high ESR group.
The mean hemoglobin concentration was significantly lower (p=0.0015) in the high compared to the low ESR group (12.2 ± 1.4 g/dl versus 13.3 ± 1.3 g/dl).
The frequency of positive temporal artery biopsy and of diagnosed giant cell arteritis was the same in the 2 groups.
Initial response to therapy, frequency of relapses, number of patients going into remission, time to remission, and daily dose of steroids were the same in both groups. (...)
Mots-clés Pascal : Pseudopolyarthrite rhizomélique, Diagnostic, Vitesse sédimentation, Epidémiologie, Fréquence, Symptomatologie, Pronostic, Personne âgée, Homme, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire
Mots-clés Pascal anglais : Polymyalgia rheumatica, Diagnosis, Sedimentation rate, Epidemiology, Frequency, Symptomatology, Prognosis, Elderly, Human, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0342231
Code Inist : 002B15D. Création : 14/12/1999.