To determine the prevalence of age-related macular degeneration (AMD) and signs of age-related maculopathy in a population-based sample of blacks and whites 40 years of age or older from East Baltimore.
Cross-sectional population-based study.
A total of 5308 black and white subjects received a screening eye examination that included fundus photography.
Stereoscopic color fundus photographs were graded for the presence and severity of drusen, pigmentary abnormalities, geographic atrophy, and choroidal neovascularization in the macula.
Drusen >= 64mum were identified in about 20% of individuals in both groups, but large drusen (>125mum) were more common among older whites (15% for whites versus 9% for blacks over 70).
Pigmentary abnormalities were also more common among older whites (7.9% for whites versus 0.4% for blacks over 70).
Age-related macular degeneration was more prevalent among whites than blacks.
The prevalence of AMD was 2.1% among whites over 70 years of age.
No cases of AMD were detected among 243 black subjects in this age group.
Logistic regression adjusting for age, sex and smoking (current, former, or never) detected an odds ratio of 4.4 (95% confidence interval : 1.5-12.4) for whites with AMD compared with blacks. (...)
Mots-clés Pascal : Dégénérescence, Macula, Age, Maryland, Etats Unis, Amérique du Nord, Amérique, Prévalence, Ethnie, Noir américain, Blanc, Etude comparative, Homme, Oeil pathologie, Rétinopathie, Maculopathie
Mots-clés Pascal anglais : Degeneration, Macula, Age, Maryland, United States, North America, America, Prevalence, Ethnic group, Black American, White, Comparative study, Human, Eye disease, Retinopathy, Maculopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0341681
Code Inist : 002B09I. Création : 14/12/1999.